(EN) We are located in the department of microbiology at the Université de Sherbrooke (Sherbrooke, Canada). If you missed some geography classes and cannot place Sherbrooke, our town is about 100 miles southeast of Montreal, just north of the Vermont/Quebec border. Our research is centered around questions dealing with the maintenance of the termini of eukaryotic chromosomes, the telomeres. For most of our work, we use genetics and molecular biology, and our model organism of choice is the yeast Saccharomyces cerevisiae. Follow our links to learn more about us. Thanks for visiting us.

(FR) Nous sommes situés au département de microbiologie et d'infectiologie de l'Université de Sherbrooke au Québec (Canada). Nous utilisons la levure Saccharomyces cerevisiae comme organisme modèle pour l'étude des mécanismes nécessaires au maintien des fins de chromosomes, les télomères. Pour ce faire, nous appliquons des techniques génétiques et de biologie moléculaire. Suivez nos différents liens (en haut) pour en savoir plus. Merci de votre visite.

(CH) Laider tuan i dae text nit ins schwiizerduetsch uebresetza. Obwohl i mi freua dass oeppert das laest, mueand iar halt Englisch koenna!!

(GR) As waer a u huara khoga'n Arbat das au n o ins Khurerduetsch z'uebersetza. Also lernan jetz halt Englisch odar vargaessans...

We are very excited to announce that registration for the 6^th Canadian Symposium on Telomeres and Genome Integrity is NOW OPEN!!

The event will take place from May 21-24, 2024 in Niagara-on-the-Lake. Our keynote speakers are Mia Levine and Alberto Ciccia.

Additional information about the meeting and registration is available on our website: event.fourwaves.com/6cstgi/pages

Congratulations to Hannah Neumann on her successful PhD thesis defense!

Congratulations to our postdoc Louise Pelle on receiving an FRQS Post Doctoral fellowship!

Congratulations to our new postdoc Gabriela Teplitz on receiving a Post Doctoral fellowship from the Centre de Recherche sur le Vieillissement!

Publication: Maturation and shuttling of the yeast telomerase RNP: assembling something new using recycled parts (Review). Bartle L, Vasianovich Y, and Wellinger RJ. Current Genetics, 2021.

Publication: Telomere Replication: Solving Multiple End Replication Problems (Review). Bonnell E, Pasquier E, and Wellinger RJ. Frontiers in Cell and Developmental Biology, 2021.

Publication: Telomerase biogenesis requires a novel Mex67 function and a cytoplasmic association with the Sm 7 complex. Vasianovich Y, Bajon E, & Wellinger RJ. eLife. 2020.
Publication: In vivo chromatin organization on native yeast telomeric regions is independent of a cis-telomere loopback conformation. Pasquier, E & Wellinger RJ. Epigenetics & Chromatin. 2020.

Congratulations to our new postdoc Louise Pelle on receiving a Post Doctoral fellowship from the Centre de Recherche sur le Vieillissement!

Congratulations to Emeline Pasquier on achieving her Ph. D!

Publication: Loss of Cdc13 causes genome instability by a deficiency in replication-dependent telomere capping. Langston R, Palazzola D, Bonnell E, et al. PLoS Genetics. 2020.

Publication: SETDB1 dependent heterochromatin stimulates alternative lengthening of telomeres. Gauchier M, Kan S, Barral A, et al. Science Advances 2019.

Congrats to Raymund for receiving the 2018 Prix Étienne-Le Bel from Université de Sherbrooke!

Congratulations to Raymund for receiving an Outstanding Contribution Award in Molecular Biology from the International Journal of Molecular Sciences!

Publication: Nuclear import of Cdc13 limits chromosomal capping. Mersaoui SY, Bonnell E, & Wellinger RJ. NAR. 2017 Feb 8.

Congratulations to Raymund for receiving the 2017 Université de Sherbrooke Prix de la recherche et de la création! https://www.usherbrooke.ca/dep-microbiologie/fr/accueil/babillard/babillard-details/article/35701/

Congratulations to the new graduates! Sofiane Mersaoui (Ph. D), Emmanuel Bajon (Ph. D), and Erin Bonnell (M. Sc.)

Welcome to our new students, Alexandra Krallis (M. Sc.) and Hannah Neumann (Ph. D.)

New funding! The lab has received a CIHR-IRSC Foundation grant. https://www.usherbrooke.ca/actualites/nouvelles/actualites/actualites-details/article/35342/

Publication: Life and Death of Yeast Telomerase RNA. Vasianovich Y & Wellinger RJ. J Mol. Biol. 2017 Jan 20.

Publication: Active Yeast Telomerase Shares Subunits with Ribonucleoproteins RNase P and RNase MRP. Lemieux B, Laterreur N, Perederina A, Noël JF, Dubois ML, Krasilnikov AS, Wellinger RJ. Cell. 2016 May 4.
Welcome to our new post-doctoral fellow, Yulia Vasianovich!

Publication: DNA damage checkpoint adaptation genes are required for division of cells harbouring eroded telomeres. Mersaoui S., Gravel S., Karpov V., Prud’Homme C., Lisby M. and Wellinger R.J. Microbial Cell. September 2015.

Publication: A Single Templating RNA in Yeast Telomerase. Bajon E, Laterreur N, Wellinger RJ. Cell Rep. July 21, 2015.

Welcome Joannie St-Germain, our new M. Sc. student!

Publication: A Function for the hnRNP A1/A2 Proteins in Transcription Elongation. Lemieux B, Blanchette M, Monette A, Mouland AJ, Wellinger RJ, Chabot B. PLoS One. May 26, 2015.

Publication: Turning telomerase into a Jekyll and Hyde case? Raymund J. Wellinger. Cancer Discov. January 2015

Congratulations to Erin Bonnell for obtaining a master student fellowship from the FRQS!

Publication: In the End, What's the Problem? Raymund J. Wellinger. Mol Cell Previews. March 20, 2014.

Congratulations to our M.Sc. student Stephen MacDonald for winning the "Best Presentation Award" at the 2nd Interdisciplinary Symposium on Cancer!

22-05-13: First Department retreat at Halte des Pèlerins

Publication: Cell cycle-dependent transcription factors control the expression of yeast telomerase RNA. Dionne I, Larose S, Dandjinou AT, Abou Elela S, Wellinger RJ. RNA. 2013 May 20.

Welcome to our new students: Emeline (M. Sc), Steve (M. Sc.), Scarlette (M. Sc) and Hannah (intern)!

Publication: A new telomerase RNA element that is critical for telomere elongation. Laterreur N, Eschbach SH, Lafontaine DA, Wellinger RJ. NAR. 2013 May 16.